小儿不完全川崎病的诊断与临床表现分析

Diagnosis and Clinical Manifestations Analysis of Incomplete Kawasaki Disease in Children

目的为了进一步提高临床对小儿不完全川崎病确诊率,避免延误治疗和不良事件的发生,探讨和分析小儿不完全川崎病临床表现和诊断方法。方法将2010年1月—2013年1月来该院就诊的350例小儿川崎病患儿作为科研对象,其中不完全川崎病86例和典型川崎病患儿264例,对比和分析两组患儿的临床表现及超声心动图的不同点。结果经过对比分析发现,不完全川崎病患儿的临床症状明显低于典型川崎病患儿的,且比较差异有统计学意义(P<0.05);而且典型川崎病患儿累及冠状动脉的几率显著低于不典型川崎病患儿的,两组比较差异有统计学意义(P<0.05)。结论不完全川崎病患儿临床症状不典型,冠状动脉受累的几率显著升高,要尽量做到早期诊断和早期治疗。

Objective To explore and analyze the clinical manifestations and diagnostic methods of pediatric incomplete Kawasaki disease so as to further improve the clinical diagnostic accuracy of the disease, and avoid delays in treatment and the occurrence of adverse events. Methods 350 cases of children with Kawasaki disease treated in our hospital during January, 2010 to January, 2013 were selected as the research object, including 86 cases of incomplete Kawasaki disease and 264 cases of typical Kawasaki disease. The differences of clinical manifestations and echocardiogram of the two groups were compared and analyzed. Results It was found that the clinical manifestations of incomplete Kawasaki disease were significantly lower than those of typical Kawasaki disease by comparative analysis, and the difference was statistically significant （P〈0.05）; the rate of arteritis involving coronary arteries of typical Kawasaki disease was significantly lower than that of atypical Kawasaki disease, the difference was also statistically signifi- cant（P〈0.05）. Conclusion The clinical symptoms of children with incomplete Kawasaki disease are atypical, and the rate of arteritis involving coronary arteries significantly increases, so the early diagnosis and treatment should be achieved as soon as possible.