阻塞性睡眠呼吸暂停低通气综合征功能性腭咽成形术的疗效

Functional palatopharyngoplasty in treatment of obstructive sleep apnea hypopnea syndrome

目的探讨功能性腭咽成形术治疗阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的疗效。方法采用功能性腭咽成形术治疗多平面阻塞OSAHS患者58例,术后6个月进行睡眠监测系统和CT上气道连续扫描复查,与术前数据比较,判定疗效。结果全部患者均未出现严重并发症,治愈3例(5.1%),显效39例(67.2%),有效8例(13.8%),无效8例(13.8%),总有效率86.2%。手术前后睡眠呼吸暂停低通气指数(apnea hypopnea index,AHI)变化有统计学差异[(65.23±21.27)次/h vs(27.82±18.45)次/h,P<0.05],最低血氧饱和度(SaO2)有显著变化[(68.35±10.16)%vs(83.73±9.68)%,P<0.05],术后腭后区及舌后区截面积明显扩大(P<0.05)。结论功能性腭咽成形术是治疗OSAHS安全、有效的方法。

Objective To study the effect of functional PPP on OSAHS. Methods We used micro-movement sensitive mattress sleep monitoring system （MSMSMS） and 256 CT to evaluate the effect of the functional PPP on OSAHS. Results Cure was attained in 3 cases （5.1%）,obvious effect in 39 cases（67.2%）,effect in 8 cases（13.8%）, no effect in 8 cases（13.8%） among 58 patients with OSAHS. AHI（P〈0.01） and SaO2（P〈0.05） showed significant difference before surgery and after surgery. The crosssection areas of the posterior areas of palate and tongue were wider than those before surgery .Conclusions Functional UPPP is a safe and efficient treatment for OSAHS.