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G蛋白信号转导调节蛋白(RGS)研究进展 被引量：7

Advances of Research on Regulators of G Protein Signaling(RGS Proteins)
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摘要 G蛋白信号转导导调节蛋白(RGS)是G蛋白信号转导通路中的负性调节因子,近年来,G蛋白信号转导途径一直是生物领域的研究热点之一。本研究总结了近年来RGS蛋白在动物和植物方面的研究进展,归纳了RGS蛋白的结构和分类;从RGS蛋白的GAPs作用、整合各种G蛋白信号系统、支架蛋白和调节细胞内运输等方面介绍了RGS蛋白的功能;阐述了RGS蛋白磷酸化、脂类修饰和RGS降解等调节机制,对RGS蛋白的深入研究有利于对信号通路的深入了解。 Regulators of G protein signaling （RGS proteins） is a negative regulator in the G protein-mediated signaling. Recently, researches were focused on G proteins and RGS proteins. This review summarized investigative progress in animals and plant in recent years. The structure and categories were described detailed. The functions including acting as GAPs, integration G protein signaling, scaffolding protein and regulating aspect protein cell transportation were analyzed. The regulatory mechanism of RGS protein was introduced from the of phosphorylation, lipidmodification, degradation of RGS proteins and so on. Deep research of the RGS was conducive to know more about the signaling pathway
作者 朱小彬 朱霞 于一帆 陈云
机构地区 扬州大学生物科学与技术学院
出处 《中国农学通报》 CSCD 2014年第6期248-253,共6页 Chinese Agricultural Science Bulletin
基金 国家自然科学基金项目"拟南芥AtRGS1蛋白在脱落酸信号转导途径中的功能研究"(30970249)
关键词 RGS蛋白 G蛋白 负性调节因子 信号转导 RGS protein G protein negative regulators signaling
分类号 S188 [农业科学—农业基础科学]
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参考文献44

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二级参考文献48

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共引文献7

同被引文献48

引证文献7

二级引证文献30

中国农学通报
2014年 第6期

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