地尔硫[艹卓]片联合谷维素治疗慢性肺源性心脏病并房颤疗效观察

目的观察地尔硫[艹卓]片联合谷维素治疗慢性肺源性心脏病并房颤的临床疗效。方法选取2008年1月至2013年1月治疗的100例慢性肺源性心脏病并房颤患者，随机分成两组，均予以常规治疗基础，对照组加用胺碘酮0．2g，每日3次，一周后改为O．2g，每日2次，口服；治疗组予地尔硫[艹卓]片30mg，谷维素100mg，每日3次，口服；两组疗程均为14d。比较两组治疗后的I晦床疗效。结果对照组的总有效率为72．91％；治疗组的总有效率为94．23％。两组比较，差异有统计学意义（P〈0．05）。两组房颤疗效比较，治疗组总有效率为96．15％，对照组总有效率为95．83％，两组比较，差异无统计学意义（P〉0．05）。不良反应率比较，对照组为27．08％，治疗组为9．61％，两组比较，差异有统计学意义（P〈0．05）。结论地尔硫[艹卓]片治疗慢性肺源性心脏病并房颤临床疗效显著，可明显改善患者的症状、体征和缓解房颤，不良反应小。

Objective To investigate dihiazem tablets combined oryzanol treatment of chronic pulmonary heart disease and atrial fibrillation clinical efficacy.Methods January 2008 January 2013 in our hospital treated 100 cases of chronic pulmonary heart disease and atrial fibrillation were randomly divided into two groups.Both groups were treated with routine therapy,based on the control group amiodarone 0.2 g3 times/day,a week later changed to 0.2,times/day,orally;treatment group to dihiazem tablets 30 mg,oryzanol 100mg,3 times/day,orally;were treated for 14 days.Compare the clinical efficacy of the two groups after treatment. Results In the control group,the total effective rate was 72.91%;treatment group,the total effective rate was 94.23%.The differ- ence was statistically significant （P 〈 0.05）.Comparison of efficacy of two groups of atrial fibrillation：the treatment group was 96.15% in the control group was 95.83%,the difference was not statistically significant （P 〉 0.05）.Adverse reaction rates compari- son：the control group was 27.08%,the treatment group was 9.61%.Conclusion Dihiazem tablets in the treatment of pulmonary heart disease and atrial fibrillation significant clinical effect,can significantly improve the patient＇s symptoms,signs and relieve a- trial fibrillation,side effects.