精神分裂症合并糖尿病患者医院感染分析

Analysis of related factors of nosocomial infections in patients with schizophrenic combined with diabetes

目的探讨精神分裂症合并糖尿病患者发生医院感染的相关因素分析,为预防医院感染提供依据。方法对医院精神科2005年1月-2010年12月住院治疗的352例精神分裂症合并糖尿病患者进行回顾性调查,对可能影响感染的因素进行分析,采用spss13.0对数据进行统计分析。结果医院感染352例精神分裂症合并糖尿病患者中发生医院感染76例,感染率为21.59%;以下呼吸道为主占51.76%,其次为上呼吸道占23.53%;分离到病原菌153株,肺炎克雷伯菌占26.80%;年龄、性别、病程、住院次数、住院天数、电休克治疗、自我照顾、体质量指数等8个因素与精神分裂症合并糖尿病患者发生医院感染有关,差异均有统计学意义(P<0.05)。结论精神分裂症合并糖尿病患者发生医院感染率高,应积极控制精神症状、防治躯体并发症、合理使用药物、控制体质量、减少电休克治疗,是防治精神分裂症伴糖尿病患者医院感染的有效措施。

OBJECTIVE To investigate the related factors of nosocomial infections in patients with schizophrenic combined with diabetes, provide some reference for the prevention of nosocomial infections. METHODS From January 2006 to December 2009 ,the clinical date of 352 patients with schizophrenic combined with diabetes were retrospectively analyzed, the risk factors that may affect the infections were analyzed. RESULTS The incidence of nosocomial infection was 21. 59%. Among the nosocomial infection, the main infections were lower respiratory infection （51. 76%） and upper respiratory infection （23.53%）. The main risk factors of nosocomial infection were age, gender, course of disease, frequency of hospitalization, hospitalization days, modified electric convulsive therapy （MECT）, self-care abilityand body mass index （BMI）（P 〈 0. 05）. CONCLUSION The incidence of nosocomial infections in patients with schizophrenic combined with diabetes is high. Controlling psychiatric symptoms actively, preventing and treating somatic complications, using drugs rationally and less or controlling weight and less MECT were the effective measures to avoid nosocomial infection in patients with schizophrenic combined with diabetes.