平坝县2009年甲型病毒性肝炎疫情综合防控措施的效果评价

Evaluation on the effect of integrated intervention measures on viral Hepatitis A in Pingba 2009

目的评估平坝县2009年甲肝应急综合措施的防控效果，为今后甲肝防控工作提供科学依据。方法采取随机整群抽样方法，调查3～15岁正常人群免疫状况及疫苗接种者的抗体阳转率，对疫情采取以甲肝疫苗应急接种为主，辅以传染源管理、饮用水消毒、食品卫生监督和健康教育等应急综合措施，比较综合措施落实前后甲肝发病率，评价其防控效果。结果平坝县3～15岁正常人群甲肝感染率55．53％（241／434），接种甲肝疫苗2个月后抗一HAVIgM阳转率77．08％（37／48）。综合防控措施保护率为86．29％，2010年发病率比2009年下降91．96％（X2=155．79，P〈0．叭）。结论平坝县甲肝发病与易感人群免疫力水平密切相关，采取以甲肝疫苗应急接种为主的综合防控措施可及时有效地控制甲肝流行。

Objective To Evaluate the effect of the integrated intervention measures in Pingba county, thus to provide with scientific basis for the making of strategies for the prevention and control on Hepatitis A. Methods With random cluster sampling, among the population at the age of 3 -15 years old, the effect of integrated intervention measures including the baseline immunity status, the positive rate of anti - HAV IgM after emer- gency immunization, cases isolation, disinfection of drinking water, supervision of food hygiene, health pro- motion, by comparing the difference between the incidence of Hepatitis A before and after the measures con- ducted. Results The infection rate of Viral Hepatitis A was 55.53% （241/434） among the people at the age 3 - 15 years old. The positive rate of anti - HAV IgM was 77.08% （37/48） two months after inocula- tion. The integrated protect rate of those intervention measures on Hepatitis A was 86. 29%. The incidence of Hepatitis A decreased 91.96% in 2010 compared with which in 2009 （X2 = 155.79, P 〈 0. 01 ） . Conclu- sions The incidence of Hepatitis A was closely related to the immunity level of target population in Pingba. Those integrated intervention measures could prevent and control the outbreaks of Hepatitis A.