疏血通联合神经节苷脂治疗急性脑梗死的疗效

Effect of Shuxuetong Combined with Ganglioside on Acute Cerebral Infarction

目的探讨疏血通联合神经节苷脂治疗急性脑梗死的临床效果。方法将70例急性脑梗死患者按随机数字表法分为观察组和对照组,每组35例。对照组给予常规治疗;观察组在对照组常规治疗的基础上给予疏血通联合神经节苷脂治疗,疗程结束后评估2组患者的临床效果,记录药物不良反应。结果观察组总有效率为100.0%,对照组总有效率为80.0%,2组比较差异有统计学意义(P<0.05)。观察组治疗后的GCS评分高于对照组(14.93±0.98比14.32±0.46)分、NIHSS评分低于对照组(5.87±1.24比9.93±1.35)分(均P<0.05)。2组均未见明显的药物不良反应。结论疏血通联合神经节苷脂治疗急性脑梗死的临床效果显著、安全,是治疗急性脑梗死较好的方法。

Objective To investigate the clinical effect of Shuxuetong combined with ganglioside on acute cerebral infarction. Methods Seventy patients with acute cerebral infarction were randomly divided into two groups,with 35 patients in each group. The control group received conventional treatment. On the basis of conventional treatment,the observation group was given Shuxuetong and ganglioside.-Clinical results were evaluated and adverse drug reactions were recorded after treatment. Results Compared with control group,the combination of Shuxuetong and ganglioside induced an elevation in total effective rate （100.0% vs 80.0%,P〈0.05）,an increase in GCS score （14.93±0.98 vs 14.32±0.46,P〈0.05）,but a decrease in NIHSS score （5.87±1.24 vs 9.93±1.35,P〈0.05）. No obvious adverse drug reactions were found in both groups. Conclusion Shuxuetong combined with ganglioside is an effective and safe treatment for acute cerebral infarction.