新生儿缺氧缺血性脑病颅内高压征的早期诊断与预后

Early Diagnosis and Prognosis of Human Neonatal Hypoxic-ischemic Encephalopathy Caused Acute Intracranial Hypertension

目的 :探讨新生儿缺氧缺血性脑病 (HIE)颅内高压症的早期诊治与预后关系。方法 :选择两组不同时期的 HIE患儿 ,两组病情分度无明显区别 (P>0 .0 5) , 组确诊时间 >4 8h, 组确诊时间≤ 4 8h,两组治疗方法基本相似。结果 : 组死亡率 39.7% ,后遗症发生率 6 .9% ; 组死亡率 14.5%与 组比 (P<0 .0 1) , 组后遗症发生率 2 .6 %与 组比 (P<0 .0 5) ,统计学有显著差异性。结论 :HIE颅内高压征如能及早诊断和治疗 。

Objective:[WT5BZ]Study the relationship between the early diagnosis,treatment and prognosis of human neonatal hypoxic ischemic encephalopathy (HIE) caused acute intracranial hypertension.[WT5HZ]Method:[WT5BZ]Select two groups of HIE patients with different periods.These two groupsdisease does not have obvious difference (P>0.05),the definite diagnose time for Group 1 is > 48 hours,and the definite diagnose time for Group 2 is ≤48 hours,the treatment method for these two groups are basically similar.[WT5HZ]Results:[WT5BZ]The deathe rate for Group 1 is 39.7% and the sequela incidence is 6.9%;The death rate for Group 2 is 14.5%,compared with Group 1 (P<0.01),the sequela incidence disease for Group 2 is 2.6%,compared with Group 1 (P<0.05),statisitics shows they have notable difference.[WT5HZ]Conclusion:[WT5BZ]If we can diagnose HIE at an early stage and treat it quickly,its death rate and sequela incidence can be obviously decreased. [WT5HZ]