手术切除联合丝裂霉素C治疗翼状胬肉的临床分析

Clinical analysis of operation excision combined with mitomycin C in treatment of pterygium

目的:评价单纯翼状胬肉切除联合应用0.02%丝裂霉素C治疗翼状胬肉的临床疗效。方法:回顾性分析手术治疗翼状胬肉患者47例(47眼)。按手术时间先后分为2组,对照组23眼:单纯翼状胬肉切除。治疗组24眼:单纯切除联合低浓度0.02%丝裂霉素C,观察2组的临床疗效,对比2组翼状胬肉术后复发率及术后并发症。结果:治疗组复发率8.3%;对照组复发率21.7%;40岁以下人群翼状胬肉术后复发率较高;2组术后均无严重的手术并发症,差异有统计学意义(P<0.05)。结论:单纯翼状胬肉切除联合0.02%丝裂霉素C治疗翼状胬肉具有操作简单、复发率低、并发症少的特点,适于临床推广。

Objective：To evaluate the clinical efficacy of simple pterygium excision combined with application of 0.02%mitomycin C in the treatment of pterygium.Methods：a retrospective analysis of 47 cases of patients with operation in treatment of pterygium （47 eyes）. According to the operation period was divided into two groups , control group：23 eyes of pterygium .The treatment group 24 eyes：simple excision combined with low concentration of 0.02%mitomycin C, observe the clinical effect of the two groups , contrast group two pterygi-um recurrence rate and postoperative complications .Results：the treatment group the recurrence rate was 8.3%;the control group the re-currence rate of 21.7%;40 years old the following the crowd pterygium recurrence rate is high;the two groups were no serious complica-tions after operation, the difference was statistically significant （P＆lt;0.05）.Conclusion：simple pterygium excision combined with 0.02%mitomycin C in the treatment of pterygium has the advantages of simple operation , low recurrence rate , less complications , suitable for clinical application .