CD117、CD13、CD33在鉴别诊断AML中的应用评价

Differential Diagnosis Value of CD117,CD13 and CD33in Acute Myeloid Leukemia

目的:探讨CD117、CD13、CD33在鉴别诊断AML中的应用评价。方法:采用流式细胞术分析510例急性白血病患者骨髓或外周血标本的免疫表型。结果:在AML中CD117、CD13和CD33的表达率依次为91.9%、91.6%和94.4%。与急性淋巴细胞性白血病相比表达率高,有显著性意义(P<0.01)。结论:CD13、CD33和CD117在AML和ALL的鉴别诊断中具有重要意义。

Objectives：To study the differential diagnosis value of CD 117 、CD13 and CD33 in acute myeloid leukemia .Methods：The peripheral blood and bone marrow of 510 cases with acute myeloid leukemia was analyzed by flow cytometry .Results：In acute myeloid leu-kemia, the percent of expression in CD117,CD13 and CD33 was 91.9%、91.6%and 94.4%.These were significantly higher compared with acute lymphoblastic leukemia （P＆lt;0.01）;Conclusion：CD117,CD13 and CD33 might be significant in differential diagnosis between acute myeloid leukemia and acute lymphoblastic leukemia .