实验性自身免疫性肌炎动物模型研究简况

Experimental Autoimmune Myositis Animal Model Research Situation

实验性自身免疫性肌炎(experimental autoimmune myositis,EAM)是一种人工诱导的类似人类多发性肌炎(poly myositis,PM)的动物模型。目前主要以大鼠、豚鼠、小鼠为实验对象,采用EAM模型复制、中医病症结合建模方法。通过实验研究选取效果明确、操作简单、模型稳定,成本较低的EAM造模方法。

Establish animal model, can the study of human related disease pathogenesis, pathological changes, as to provide theoretical basis for looking for effective treatment. Experimental autoimmune myositis （ EAM ） systems in Europe with operation is a kind of artificial induction of similar human multiple myositis （ PM ） animal model. At present mainly in rats, guinea pigs, mice as experimental object, USES the EAM model replication method, condition of traditional Chinese medicine combined with modeling, etc. By experimental study on selecting effect is clear, simple operation, stable model, lower cost of EAM building methods.