UBIO联合中药治疗口腔糜烂型扁平苔藓的疗效研究

The research of curative effect of UBIO combining with Chinese traditional medicine therapeutics on oral cavity anabrosis lichen planus

目的 探讨紫外线照射充氧自血回输 (UBIO)加中药对口腔糜烂型扁平苔藓的疗效作用。方法 把口腔扁平苔藓病人随机分为两组 ,分别在治疗前后测定血液流变学、红细胞免疫、甲皱微循环等指标。结果 U BIO组治疗后与治疗前相比管袢长度、流速变慢的异常率、低切全血粘度、高切全血粘度、血浆粘度、血沉、C3b R花环率、C3b 1C花环率均有显著差异 (P <0 .0 1) ,袢顶管径的异常率与治疗前相比也有明显变化 (P <0 .0 5 ) ;中药组治疗后与治疗前相比血浆粘度、血沉明显降低 (P <0 .0 1) ,而且管袢长度、流速变慢的异常率低于治疗前 (P <0 .0 5 )。结论 UBIO加中药对口腔扁平苔藓有显著疗效 ,明显优于纯中药治疗。

Objective Objective To study the therapeutic effects of UBIO combining with Chinese traditional medicine on oral cavity anabrosis lichen planus. Methods The patients suffering from OLP were randomly divided into two groups:Chinese traditional medicine and UBIO plus Chinese traditional medicine.The indexed of blood rheology、erythrocytic immunity、nail cockle microcirculation were examined before and after therapy in two groups. Results There were significant difference in indexes of the abnormality percentage of the flow、low shear whole blood viscosity、high shear whole blood viscosity、plasma viscosity、ESR、the wreath percentage of RBC C3 R、the wreath percentage of RBC 1C between before and after therapy in UBIO group.The abnormality percentage of diameter of ansa top in UBIO group also showed marked change( P < 0.05 ).The plasma viscosity and ESR were decreased markedly in Chinese traditional medicine group after treatment( P < 0.01 ),and the abnormality percentage of the length of capillary ansa and velocity of blood flow were also decreased( P < 0.01 ),and the abnormality percentage of the length of capillary ansa and velocity of blood flow were also decreased( P < 0.05 ). Conclusion UBIO plus Chinese traditional medicine has marked curative effect on oral cavity anabrosis lichen planus,and it is better than simple Chinese traditional medicine on that.