银杏达莫注射液治疗急性重型颅脑创伤54例

Treatment of Acute Severe Traumatic Brain Injury by Yinxingdamo for 54 Cases

目的观察银杏达莫对急性重型颅脑外伤的治疗效果。方法选取108例符合标准的急性重型颅脑外伤患者随机分为2组,银杏达莫为治疗组54例,常规治疗基础上加用银杏达莫注射液每次20ml,每日2次,加入0.9%氯化钠注射液500ml中静脉滴注,2~3h滴完,应用10天。对照组54例：采用常规治疗,不给予脑保护治疗。记录两组患者治疗后10天的脑水肿程度、治疗前和治疗后第10天的GCS评分及治疗后3个月时的GCS评分。结果治疗后两组患者脑水肿程度有显著性差异,两组GCS评分均有改善,但治疗组更为显著,3个月时的GCS评分有显著性差异。结论应用银杏达莫治疗急性重度颅脑损伤患者疗效显著,缩短昏迷时间,促进患者神经功能恢复,降低伤残率,促进患者神经功能恢复,改善预后,且副作用少,安全可靠。

Objective To observe the therapeutic effect of ginkgo leaf extract and dipyridamole injection on acute severe brain injury. Methods 108 cases of acute severe craniocerebral trauma in accordance with the standards were randomly divided into 2 groups,ginkgo leaf extract and dipy- ridamole treatment group 54 cases,conventional treatment combined with ginkgo leaf extract and dipyridamole injection 20 ml each time,2 times a day,adding 500ml normal saline intravenously,2 - 3h finished,applied for 10 days. 54 cases of the control group： conventional treatment,do not give the brain protective therapy. The degree of cerebral edema,recorded 10 days after treatment in two groups of patients before and after the treatment in section 10d of the GCS score and the GOS score of 3 months after treatment. Results There were significant difference between the two groups in the degree of brain edema after the treatment,GCS scores of the two groups were improved,but the treatment group is more signifi- cant,there is significant difference in GOS scores at 3 months. Conclusion The application of ginkgo leaf extract and dipyridamole in treatment of acute patients with severe brain injury was significantly,shorten the coma time,promote the recovery of neurological function,reduce the rate of disability,promote the recovery of neural function in patients,improve the prognosis,and less side effects,safe and reliable.