结直肠癌肝转移的诊断和治疗

The early diagnosis and treatment of liver metastasis in colorectal cancer

目的 总结和分析结直肠癌转移的诊断和治疗。方法 回顾分析 39例结直肠癌肝转移的病人 ,通过癌胚抗原、B超CT等检查 ,提出诊断措施 ,对肝转移灶行根治性切除 6例与肝转移灶未手术仅行TACE、HAI等综合治疗 2 4例进行 3年、5年生存率比较。结果 早期诊断肝转移灶并得到根治性手术的 6例 ,3年、5年生存率分别为 6 6 .7%和 33.3% ,较未手术仅综合治疗的 2 4例的生存率 12 .5 %和 0明显增高。结论 结直肠癌肝转移应重视诊断同时根治性手术切除肝转移灶效果最佳。

Objective To study the early diagnosis and treatment of liver metastasis in colorectal cancer(CRC). Methods The clinical data of 30 patients with liver metastasis of CRC were retrospectively analyzed. The diagnosis were gained by determination of CEA and examinations of ultrasonography and computed tomography, ect.The 3 year and 5 year survival rate was compared between the 6 cases undergoing radical operation and 24 unoperated cases only undergoing TACE, HAI treatment.Results The 3 year and 5 year survival rate of the 6 patients with early diagnosis and radical operation was 66.75% and 33.3% respectively, significantly higher than that of the 24 unoperated cases ( 12.5% and 0 respectively). Conclusions The early diagnosis and radical operation might play an important role in the treatment of CRC with liver metastasis.