埋植式药泵在肝癌治疗中的应用

Application of implantable infusion pump in the treatment of lvier carcinoma

目的 探讨对不能切除的肝癌患者术中应用埋植式药泵治疗的临床意义。方法 对2 8例肝癌患者 ,术中作肝动脉和门静脉插管并皮下埋植药泵 ,术中、术后经药泵进行肝脏局部灌注化疗取得了较好的疗效。结果 本组治疗后有效率为 6 4.2 % ,其中生存时间小于 6个月 15例 ,6～12个月 10例 ,12个月以上 3例其中 1例存活 2 2个月以上。结论 肝动脉局部灌注化疗对不能手术切除的晚期肝癌 ,作为治疗手段不失为一种有效的方法。

Objective To investigate the efficacy of implantable infusion pump in the treatment of un resectable liver cancer. Methods Twenty eight patients with liver cancer were subjected to the subcutaneous implantation of chemotherapy infusion pump into hepatic artery and portal vein during operation, and hepatic local perfusion chemotherapy via the pump was performed during and after operation. Results In this group, the total effective rate was 64.2% . The survival time was less than 6 months in 15 cases, 6 to 12 months in 10 cases and over 12 months in 3 cases. Conclusions The local infusion chemotherapy via hepatic artery and portal vein was an effective therapy for those who could not undergo the resection of advanced liver cancer.