摘要
为了解江苏省健康儿童脊髓灰质炎 (脊灰 )的免疫状况 ,进行了 0~ 2月龄婴儿口服脊灰疫苗 (OPV)免疫成功率监测 ,6月龄~、1岁、2岁、3岁、4~ 9岁儿童脊灰抗体水平监测。 1996、1997、1999年儿童OPV免疫成功率监测结果是 :Ⅰ型 94 6 %~ 98 2 % ,Ⅱ型 98 2 %~ 10 0 0 % ,Ⅲ型 92 9%~ 10 0 0 %。 1995~ 1999年健康儿童脊灰抗体水平监测结果是 :中和抗体阳性率Ⅰ型为 92 3%~ 10 0 0 % ,Ⅱ型 94 2 %~ 10 0 0 % ,Ⅲ型 94 2 %~ 10 0 0 % ;中和抗体几何平均滴度Ⅰ、Ⅱ、Ⅲ型分别为 1∶5 5 6~ 1∶35 9 2、1∶110 2~ 1∶188 0、1∶70 8~ 1∶10 8 4。说明通过OPV的常规免疫和强化免疫 。
In order to understand the polio immune level of healthy children in Jiangsu Province, we conducted a survey to find out the immune successful rate of oral polio vaccine (OPV) to 0~2 month old infants and the polio neutralizing antibody level among 6~12 month old to 9 year old children. The results showed that the OPV immune successful rates of infants ranged from 94.6%~98.2%, 98.2% ~100%, 92.9%~100% for Polio Ⅰ, Ⅱ, Ⅲ respectively observed in 1996, 1997 and 1999. The neutralizing antibody positive rates in healthy children in 1995~1999 ranged from 92.3%~100% for polio Ⅰ, 94.2%~100% for Polio Ⅱ, 94.2%~100% for polio Ⅲ and the GMT were 1∶55.6~1∶359.2, 1∶110.2~1∶188.0, 1∶70.8~1∶108.4 for polio Ⅰ, Ⅱ, Ⅲ respectively. These results revealed that a firm protection against poliomyelitis in children in Jiangsu Province has been established through routine and supplementary immunization of OPV.
出处
《中国计划免疫》
2001年第1期23-25,共3页
Chinese Journal of Vaccines and Immunization
关键词
脊髓灰质炎
中和抗体
监测
江苏
疫苗
Poliomyelitis
Neutralizing antibody
Vaccine
Surveillance