原发性干燥综合征合并两肺进行性多发性囊肿1例

A case of primary Sj, gren's syndrome with progressive multiple cysts of lungs

患者女性， 32岁。两下肢瘀点瘀斑伴膝关节疼痛 2月入院。 10余年前开始出现口干、眼干，近 5年伴全身皮肤干燥。类风湿因子 1∶ 2000(＋ )， IgG 22.38g/L， IgA 7.23g/L,ANA 1∶ 320(＋ ),La(SSB)(＋ )。唇腺活检病理诊断符合干燥综合征。唾液腺动态功能 ECT检查示 (1)双颌下腺无功能； (2)双腮腺浓聚功能及排泄功能降低。多次胸部 X线检查，两肺呈进行性多发性薄壁囊肿。

A 32- year- old woman complained of petechiae of the lower limbs with pain of knee joints for two months. About ten years ago, the patient had been shortage of saliva and tear. For recent five years, she felt the drying of skin all over the body. Laboratory exam showed that rhumatoid factor was 1∶ 2000, ANA titers 1∶ 320, IgG 22.38g/L, IgA 7.23g/L and La(SSB) positive .Pathological exam of lip area tissue supported the diagnosis of Sj, gren s syndrome. ECT exam for dynamic function of salivary gland showed no function of bilateral submaxillary salivary glands， decreased concentration and drainage function of bilateral parotid salivary glands.Chest X ray exam for several times confirmed that there were progressive multiple cysts with thin wall in both lungs.