米索前列醇在晚期妊娠中的应用

Application of Misoprostol in Late Pregnancy

目的探讨米索前列醇用于晚期引产的安全性及效果.方法对201例妊娠35～43周有引产指征的产妇随机分为2组.米索前列醇组102例,对照组99例,分别用米索前列醇50 mg阴道后穹窿用药引产及催产素引产.结果2组病人母婴并发症无明显差别,而米索前列醇可促进宫颈成熟,缩短引产至分娩时间,减少催产素用量.结论米索前列醇引产安全有效,临床上正逐步取代传统的催产素静点引产.

Objective To study the efficiency and safety of misoprostol for labor induction in late pregnancy.Methods 201 pregnants (35～43 week) women with indication for labor induction were randomly assigned two groups.There were 102 cases in misoprostol group:50?mg misoprostol was placed in the posterior vaginal fornix for labor induction,and there were 99 cases in the control group:used oxytocin for labor induction.Results No significant differences in maternal or fetal complications were observed in two groups.Misoprostol may ripen the cervix,and the time from the beginning of induced labor to the labor and oxytocin were shorter than the control group.Condusion Misoprostol have great effect and safety,the intravenous oxytocin drip is being replaced by misoprostol for labor induction.