和胃降逆法对反流性食管炎临床症状及内镜分级的影响

Effects of Therapy of Stomach-Regulating and Qi-lowering on Clinical Symptoms and Endoscopic Grade of Reflux Esophagitis

目的:研究和胃降逆法对反流性食管炎的临床症状及食管黏膜内镜分级的影响。方法:选择120例反流性食管炎患者,分为中医治疗组、西医治疗组。中药治疗组以和胃降逆法治疗,选用和胃降逆方1包;西药治疗组以奥美拉唑胶囊20 mg。两组均1日2次,共8周。反流性食管炎患者治疗前后均行胃镜检查及食管黏膜病理活检。观察和胃降逆法对反流性食管炎患者的临床疗效及食管黏膜内镜改变。结果:和胃降逆法能明显改善反流性食管炎的临床症状,其总有效率达96.77%,与西药奥美拉唑的总有效率(94.83%)相当;同时能明显改善反流性食管炎的食管黏膜内镜分级积分。结论:和胃降逆法能明显改善反流性食管炎患者的临床症状,并能明显改善食管黏膜内镜分级改变。

Objective ： To investigate the effects of the therapy of stomach - regulating and Qi - lowering on the clinical symptoms and endoscopic grade of reflux esophagitis. Methods ： 120 patients with reflux esophagitis were divided into two groups ： Chinese medicine group and western medicine group. The Chinese medicine group was treated with the therapy of stomach - regulating and Qi - lowering. These cases were given 1 dose of Chinese herb of stomach - regulating and Qi - lowering, while the western medicine group was treated with Omeprazole capsule. The medicine for two groups was taken twice a day for 8 weeks. AI｜ patients had examination of gastroscope and biopsy of esophageal mucosa before and after treatment. The clinical symptoms and endoscopic grade of esophageal mucosa were observed after the therapy of stomach - regulating and Qi - lowering in the patients of reflux esophagitis. Results ： The therapy of stomach - regulating and Qi - lowering could ameliorate the clinical symptoms of reflux esophagitis, and the total effective rate of it was 96.77%, which was equal to those of the Omeprazole（94.83% ）. Meanwhile, it could obviously improve the endoscopic grade of esopha- geal mucosa of reflux esophagitis. Conclusion ： The therapy of stomach - regulating and Qi - lowering has obvious clinical symptoms in reflux esophagitis, and could obviously ameliorate the endoscopic grade of esophageal mucosa of reflux esophagitis.