环己烷氧化反应:有机小分子的催化作用

Cyclohexane oxidation:Small organic molecules as catalysts

考察了酮、醛、酯、醇与胺等几类有机小分子在环己烷氧化反应中的催化作用.结果表明,有机小分子催化剂的活性与其极性的强弱、与环己烷形成氢键的强弱、α氢的活性及清除自由基的能力有关.因此,对于环己烷氧化反应,溶剂很可能存在催化作用.三丙胺在环己烷氧化反应中表现出较高的催化活性,具有进一步开发应用的前景.

The catalytic activity of several small organic molecules including ketones, aldehydes, esters, alco-hols and amines toward cyclohexane oxidation was investigated. The catalytic activity was found to be closely related to polarity, α-H activity, the strength of hydrogen bond formed with cyclohexane and the radical scavenging capability of these molecules. Based on the obtained results, the catalytic role of the organic solvent must be considered for cyclohexane oxidation. Tripropylamine has very high activity in cyclohexane oxidation and it might be further developed as a promising small-molecule organocatalyst for future application.