摘要
甲状腺癌的患病率逐年增加,越来越多的研究表明肥胖可能增加其患病风险,且女性肥胖人群的甲状腺癌患病率显著增加.目前认为,胰岛素抵抗、高胰岛素血症、脂肪因子、促甲状腺激素和雌激素是较有可能参与肥胖致甲状腺癌过程的重要因素.但仍需要更多研究明确肥胖对甲状腺癌的影响及其机制,这将有助于肥胖和甲状腺癌的防治.
Along with the rising prevalence of thyroid cancer,more and more evidence showed that obesity might play an important role in thyroid tumorigenesis.This association is stronger in female.Insulin resistance,hyperinsulinemia,adipokines,thyrotropin and estrogen may participate in the development of obesity-related thyroid cancer.However,further research is required to clarify the effects of obestity on thyroid tumour and the underlying mechanism,which is essential to the treatment and prevention of both diseases.
出处
《国际内分泌代谢杂志》
北大核心
2014年第2期87-89,共3页
International Journal of Endocrinology and Metabolism
关键词
肥胖
甲状腺癌
Obesity
Thyroid cancer
