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丙型肝炎病毒动物模型研究进展

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摘要 丙型肝炎病毒(hepatitisCvirus,HCV)是一个约9.6kb长的单股正链RNA病毒,属于黄病毒科。HCV感染可造成慢性肝炎,该病程特点是进行性肝脏损伤,往往通过几十年的进展,从肝纤维化到肝硬化,最终发展为肝细胞癌(HCC)。尽管干扰素(INF)联合利巴韦林是目前治疗慢性丙型肝炎最有效的方法.但仍不理想,且不同基因型的应答率之间存在较大差异,价格也昂贵。因此,研发HCV疫苗和创新治疗方法越来越引起人们重视。
出处 《现代医药卫生》 2014年第6期852-855,共4页 Journal of Modern Medicine & Health
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