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血尿酸水平在慢性心力衰竭患者中的变化及临床意义 被引量:2

Clinical significance of serum uric acid in patients with chronic heart failure
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摘要 目的观察血清血尿酸水平在慢性心力衰竭(CHF)患者的中的变化及临床意义。方法选取2010年5月-2011年10月收治的98例CHF患者,按心功能分级分组,并测定心衰患者治疗前后血清尿酸水平,与健康对照组的血清尿酸水平相比较。结果按心功能分级组比较血清尿酸水平差异显著(P<0.01);血尿酸水平在CHF纠正后显著降低较治疗前有明显差异(P<0.01)。结论血尿酸浓度与心功能呈负相关,心功能越差血尿酸浓度越高,随心功能逐渐改善血清尿酸浓度逐渐下降,动态检测血清尿酸浓度是判断CHF疗效的有效指标,是预测不良事件的一个有意义的生化指标。 【Objective】To investigate the chronic heart failure(CHF)level of serum uric acid changes and clinical significance.【Methods】May 2010 to October 2011 98 patients were treated according to CHF NYHA classification groups. and with the healthy control group compared with the serum uric acid 1evels.【Resluts】According to NYHA classification group differences in serum uric acid levels were significantly(P0.01); heart failure corrected significantly lower serum uric acid 1evel significant difference compared with before treatment(P0.01).【Conclusion】The more severe heart failure.higher serum uric acid concentrations,heart function improved significantly decreased serum uric acid levels,dynamic testing is to determine serum uric acid in the treatment of heart failure,a significant chemical and biological indicator.
作者 丛海霞 高华
出处 《中国医学工程》 2014年第2期6-6,8,共2页 China Medical Engineering
关键词 慢性心力衰竭 血尿酸 黄嘌呤氧化酶 Chronic heart failure Uric acid Xanthine Oxidase
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参考文献8

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