阿司匹林联合血塞通胶囊在脑梗死防治中的安全性

The security of Xuesaitong capsule combined with aspirin in therapy of cerebral infarction patients

目的本研究观察本院常用的活血化瘀中成药血塞通胶囊与阿司匹林联合使用的安全性,旨在指导我院安全用药。方法选100例来我院就诊符合脑梗死诊断标准的患者随机分为两组,拜阿司匹林组、血塞通胶囊联合拜阿司匹林组,观察血塞通胶囊与阿司匹林联用的安全性。结果观察组及对照组治疗后较治疗前凝血相关指标(PT、APTT、FIB、D-Di),潜在出血事件相关指标(PLT、PAGT、MAR),出血事件等观察指标差别均无统计意义(P>0.05),且不良反应少。因此,阿司匹林与血塞通胶囊联合使用不会增加出血风险性。结论阿司匹林与血塞通胶囊联合使用无安全隐患,不会增加患者出血风险性。

【Objective】Observe the security of Xuesaitong capsule of Chinese herbs injection for activating blood circulation combined with aspirin in therapy of cerebral infarction patients.【Methods】On prospectively study that choosing one hundred patients who accord with the diagnostic criterions of the apoplexy both Western medicine and Chinese traditional medicine, then distribute 50 patients into the Aspirin group at random and 50 patients into Xuesaitong capsule combined with Aspirin group.And observe the security of Xuesaitong capsule combined with Aspirin in therapy of cerebral infarction patients.【Resluts】The results of prospectively study display PT, AP, FIB,D-Dimer do not have significantly change in both observation group and control group after treatment（P0.05）. And rare have adverse reaction. Its effect better than control group but not significantly and do not increase the risk factors of hemorrhage.【Conclusion】 Xuesaitong capsule combined with Aspirin in therapy of cerebral infarction patients do not increased the risk factors of hemorrhage.