摘要
Spiro heterocycles frequently occur in bioactive molecules. In the pursuit of neonicotinoids with spiro hererocycles, three types of novel neonicotinoids with spirobenzofuranone, spirooxindole or spiroacenaphythylenone framework were designed and synthesized. Insecticidal evaluation showed that some of spirobenzofuranone containing neonicotinoids exhibited moderate activity against cowpea aphid, armyworm or brown planthopper.
Spiro heterocycles frequently occur in bioactive molecules. In the pursuit of neonicotinoids with spiro hererocycles, three types of novel neonicotinoids with spirobenzofuranone, spirooxindole or spiroacenaphythylenone framework were designed and synthesized. Insecticidal evaluation showed that some of spirobenzofuranone containing neonicotinoids exhibited moderate activity against cowpea aphid, armyworm or brown planthopper.
基金
financial supported by National Basic Research Program of China(973 Program,No.2010CB126100)
National High Technology Research Development Program of China(863 Program,No.2011AA10A207)
Key Projects in the National Science & Technology Pillar Program(No.2011BAE06B05)
National Natural Science Foundation of China(No.21372079)
Shanghai Education Committee(No.12ZZ057)
the Fundamental Research Funds for the Central Universities
partly supported by Australia DC Foundation
