B超引导经皮肝穿射频治疗肝癌24例临床研究

Clinical study of ultrasound-guided percutaneous radipfrequency ablation in 24 cases with liver cancer

目的探讨肝癌患者实施经皮肝穿射频治疗的效果。方法回顾性分析2006年11月～2011年1月本院24例肝脏恶性肿瘤患者行B超引导经皮肝穿射频治疗的临床资料。结果24例患者中，16例患者15min吲哚靛青绿储留率（ICGR15）〈10％，5例10％～20％之间，3例〉20％；甲胎蛋白提示阳性患者经治疗后转为阴性的有75．0％，呈明显下降的有25．0％；CT复查显示肿瘤缩小，完全凝固性的坏死率是87．5％。结论对于肝癌患者，尤其是重度肝硬化、肝功能较差、不耐手术、术后复发者，实施RF治疗不仅创伤小，而且方便、安全，疗效确切，应予临床合理推广。

Objective To explore the clinical effect of ultrasound-guided percutaneous radiofrequency ablation in treating patients with liver cancer. Methods Clinical data of 24 patients with liver cancer who were treated using ultrasound-guided percutaneous radiofrequency ablation in our hospital frmn November 2006 to January 2011 was retrospectively analyzed. Results In 24 patients, the indocyanine green retention rate in 15 minutes （ICGR 15） was less than 10% in 16 cases,10%-20% in 5 cases and more than 20% in 3 cases. 75.0% of AFP-positive patients turned to be negative after the treatment and 25.0% of patients had significant decrease.CT scan results showed tumor shrinkage and the necrosis rate of complete coagulation was 87.5%. Conclusion Radiofrequency ablation should be promoted clinically with minimum invasion,good safety and efficacy in the treatment of liver cancer, especially for those patients with severe liver cirrhosis, poor liver function,non-resistance to surgery and postoperative occurrence.