长爪沙鼠在病原感染研究中的应用

Application of mongolian gerbil as animal model in pathogenic infection and immunological studies

长爪沙鼠对多种病原易感,某些病原感染后的疾病特征与人类相似,因而广泛应用于感染性疾病动物模型,为感染性疾病的病理学特征、发病机制、免疫学诊断和药物研发等研究提供了重要材料。本文简要综述了长爪沙鼠在微生物和寄生虫感染等相关研究中的应用,以期为长爪沙鼠的开发应用提供借鉴。

Mongolian gerbil （Meriones unguiculatus） has many specific biological characteristics and is permissive to several infections, and has been widely used for infectious diseases models in studies on infectious of viral, bacterial and parasitic. In this article, we briefly introduce the application of gerbils in the infection of microorganisms and parasites for the past few years.