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甲状腺疾病与女性生殖 被引量：6

Thyroid Diseases and Femal Reproduction
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摘要 正常的甲状腺功能状态是维持女性生殖能力的一个重要因素;甲状腺激素直接或间接参与调节女性生殖功能。甲状腺机能障碍会影响性激素结合球蛋白(SHBG)和催乳素(PRL)水平,从而改变类固醇激素代谢和下丘脑-垂体-卵巢轴的功能,导致凝血功能障碍和各种生殖问题,如月经紊乱、排卵障碍、不孕、流产、早产等。甲状腺机能障碍通过适当的临床干预可能恢复正常的月经周期,并改善生殖功能。 Normal thyroid function is essential to maintain the female reproductive ability. Thyroid hormones are directly and indirectly involved in the regulation of female reproductive function. Thyroid dysfunction affects sex hormone binding globulin （SHBG） and prolactin （PRL） levels, alteres the metabolism of steroid hormones and the function of hypothalamic-pituitary-ovary axis, and causes coagulation dysfunction, which result in various reproductive problems such as menstrual disorders, ovulation disorder, infertility, abortion, premature birth, etc. Proper clinical intervention may restore the normal menstrual cycle, and improve fertility and the outcome of pregnancy.
作者 王亚茹 张洁 吴隆琦 邵小光
机构地区 大连市妇女儿童医疗中心
出处 《生殖与避孕》 CAS CSCD 2014年第3期232-236,共5页 Reproduction and Contraception
关键词 甲状腺功能亢进症(HT) 甲状腺功能减退症(HoT) 甲状腺自身免疫 生殖 辅助生殖技术(ARTl hyperthyroidism （HT） hypothyroidism reproductive technology （ART） （HOT） thyroid autoimmunity reproduction assisted
分类号 R581 [医药卫生—内分泌] R71 [医药卫生—妇产科学]
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参考文献38

  • 1Kim NY, Cho HJ, Kim HY, et al. Thyroid autoimmunity and its association with cellular and humoral immunity in women with reproductive failures. Am J Reprod Immunol, 2011, 65 (1):78-87.
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二级参考文献59

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共引文献39

同被引文献50

引证文献6

二级引证文献35

生殖与避孕
2014年 第3期

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