585nm/1064nm双波长复合激光预防手术后瘢痕增生的自体对照观察

Self-control Study of 585nm/1 064nm Dual-wavelength Laser in the Prevention of the Hyperplasia of Postoperative Scars

目的观察585nm/1 064nm双波长复合激光预防手术后瘢痕增生的疗效及安全性。方法 13例术后瘢痕的患者将其瘢痕皮损按其长轴平均分为两部分,随机将一端接受585nm/1 064nm双波长复合激光治疗,另一端不做任何处理作为对照组。治疗后的3,6和12个月进行随访,采用Vancouver瘢痕评分量表分别对治疗组和对照组进行评分评估疗效,并观察不良反应。结果在治疗3,6和12个月后,治疗组的Vancouver瘢痕评分分别为4.85±1.07,3.15±0.99和1.54±1.13,对照组分别为8.08±1.38,6.92±1.75和5.31±2.14,两组间差异均有统计学意义。结论 585nm/1 064nm双波长复合激光对术后瘢痕增生有预防作用,不良反应轻。

Objective To observe the efficacy and safety of 585nrn/1 064nm dual-wavelength laser in the prevention of the hyperplasia of postoperative scars. Methods Postoperative scars of thirteen cases were averagely separated to two parts longitudinally. One part was randomly chosen as treatment group and was treated with 585nm/1 064nm dual-wavelength laser,and the other part remained untreated as control group. All patients were followed up 3,6 and 12 months after treatment to evaluate the effectiveness by Vancouver General Hos- pital Burn Scar Assessment score. Meanwhile, adverse event was also recorded. Results The Vancouver General Hospital Burn Scar Assessment score of treatment group were 4.85±1.07,3.15±0.99 and 1.54±1.13 in 3,6 and 12 months after treatment,respectively,while the control group were 8.08±1.38,6.92 ＋ 1.75 and 5.31±2. 14 respectively. There were statistically significant differences between the treatment group and the control group among the three follow-ups. Conclusion 585nm/1 064nm dual-wavelength laser is an effective and safe treatment for the prevention of the hyperplasia of postoperative scar, and worthy of extensive clinical application.