非心电门控低剂量平扫MDCT评价心外膜脂肪组织

Quantification of Epicardial Adipose Tissue in Non-ECG-gated Low-radiation-dose MDCT

目的:采用非心电门控低剂量平扫MDCT定量EAT容积并评价与冠脉CTA图像所测量EAT容积值的相关性和一致性。方法:对61例受检者行回顾性心电门控技术冠状动脉CTA和胸部低剂量肺癌筛查CT平扫。采用GE AW4.4工作站手动勾画心包线并计算两种扫描方式所测EAT容积。非门控低剂量平扫CT图像脂肪组织阈值设定范围为-195~45 Hu;冠脉CTA图像脂肪组织阈值设定范围分为5组,分别为-175^-25 Hu、-170^-20 Hu、-165^-15 Hu、-160^-10 Hu、-155^-5 Hu。结果:非门控低剂量平扫CT图像所测值与冠脉CTA图像所测值有很好的相关性(r分别为0.996、0.997、0.997、0.997、0.996)。当冠脉CTA图像脂肪组织阈值范围取值为-165^-15 Hu时,所测的EAT容积与非门控低剂量平扫CT图像所测值无统计学差异(P=0.125)。结论:低剂量非心电门控平扫CT图像能够进行EAT容积的评价,且与通常使用的冠脉CTA图像评价结果相比有较好的相关性和一致性。

Objective： To quantify the EAT volume in non-ECG-gated low-radiation-dose MDCT and assess the relationship of EAT volume in non-ECG-gated MDCT in comparison with ECG-gated Coronary CTA. Method： In all,61 patients were enrolled in this study and underwent retrospective ECG-gated coronary CTA and non-ECG-gated low-radiation-dose MDCT for lung cancer screening. The EAT volume was calculatgd through depicted the epicardium with AW4.4 workstation （GE）. The threshold of EAT quantification in non-ECG-gated CT was -195--45 Hu. A total of five programs of the thresholds of EAT quantification in coronary CTA would be built （-175--25 Hu, -170--20 Hu, -165--15 Hu, -160--10 Hu, -155--5 Hu respectively）. Result： The EAT volume quantification in non-ECG-gated MDCT had a significant relationship with the quantifications in ECG-gated Coronary CTA （r = 0.996, r = 0.997, r = 0.997, r = 0.997, r = 0.996 respectively）. When the threshold of EAT quantification in ECG-gated Coronary CTA was -165--15 Hu, no significant difference was observed for EAT volume quantification with non-ECG-gated MDCT with respect to ECG-gated Coronary CTA （P = 0.125）. Conclusion： Non-ECG-gated low-radiation-dose MDCT allows quantifying EAT with almost the same consistency and correlation as using ECG-gated Coronary CTA.