心肌损伤生化标志物在急性缺血性胸痛诊断中的临床意义

The Clinical Significance of the Biochemical Markers of Myocardial Damage Material in the Diagnosis of Acute Ischemic Chest Pain

目的:探讨心肌损伤生化标志物(cTnI、CK-MB、CRP、DD、UA)在急性缺血性胸痛诊断中的临床意义。方法:比较2010年11月-2012年12月收治的急性心肌梗死组(A组,n=80)、心绞痛组(B组,n=80)和正常对照组(C组,n=80)患者血清cTnI、CK-MB、DD、CRP、UA的含量。结果:A组的cTnI、CK-MB、CRP检测阳性率均明显高于B组和C组(P均<0.05),A组的DD、UA检测阳性率也明显高于C组(P均<0.05)。结论:cTnI、CK-MB、CRP、DD、UA各自的特点不同,联合检测心肌损伤生化标志物在急性胸痛诊断中具有重要的临床意义。

Objective：To explore the clinical significance of the biochemical markers of myocardial damage material （cTnI, CK-MB, CRP, DD, UA） in the diagnosis of acute ischemic chest pain. Method： The serum cTnI, CK-MB,DD,CRP and UA were compared among the acute myocardial infarction group（group A,n=80）,angina group （group B,n=80） and normal control group （group C,n=80 ） from Nov 2010 to Dec 2012. Results： The positive rate of serum cTnI, CK-MB and CRP in the group A were significantly higher than those in the group B and the group C, all P 〈 0.05, and the positive rate of serum DD and UA in the group A were significantly higher than those in the group C, both P 〈 0.05. Conclusion： The serum cTnI,CK-MB,CRP,DD and UA are of different characteristics,and them are combined detection has important clinical significance in the diagnosis of acute chest pain.