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重视非酒精性脂肪肝和2型糖尿病的关系研究 被引量:28

Advancement of researches on association of non-alcohoUc fatty liverdisease with type 2 diabetes mellitus
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摘要 非酒精性脂肪肝病(NAFLD),是一种除外过量饮酒和其他明确损肝因素所致的、以肝脏脂肪积聚为主要病理表现的慢性肝脏疾病,也是代谢综合征的肝脏表现。NAFLD不仅与2型糖尿病(type2diabetesmellitus,T2DM)、动脉粥样硬化性心血管疾病密切伴随,而且是这些相关疾病的独立预测因素。在T2DM患者中,NAFLD的患病率可高达70%[1],T2DM一旦合并NAFLD,可以进一步恶化糖代谢,并且增加非酒精性脂肪性肝炎(NASH)的发病风险,加速其向肝纤维化、肝硬化的进展。NAFLD和T2DM形成恶性循环,造成糖代谢紊乱和不良肝病结局。我们要重视T2DM患者的肝病状况、肝病进展,预防肝脏疾病不良结局和后果.
作者 高鑫 王杉杉
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2014年第3期161-164,共4页 Chinese Journal of Hepatology
关键词 脂肪肝 糖尿病 非胰岛素依赖型 尿病并发症 非酒精性脂肪性肝炎 Fatty liver Diabctesmellitus, non-insulin-dependent Diabetes complications Non-alcoholic steatohepatitis
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