摘要
多模态显像技术中的PET/CT和SPECT/CT现已广泛用于临床,而PET/MRI也已有商业成机。SPECT灵敏度高,应用基础广泛,其示踪剂适应面广、获取相对容易,SPECT技术与高分辨率MRI相结合的SPECT/MRI具有广泛应用前景。本文对该领域在系统结构设计、图像配准与校正及应用于动物实验的多模态纳米分子探针方面的研究进展进行综述。
PET/CT and SPECT/CT, as multi-modality imaging techniques, have been widely used in routine clinical works. The application of commercial PET/MRI imaging scanner in clinical has also been approved. SPECT is characterized with high sensitivity and wide application, together with the extensive application and easy accessibility of its radiola- beled tracers. SPECT/MRI, which combines SPECT with high resolution MRI, will be widely used in the future. The re- search progresses in these fields mainly focused on systematic structure design, image co-registration and molecular nanop- articles used in animal experiments were reviewed in this paper.
出处
《中国医学影像技术》
CSCD
北大核心
2014年第3期474-477,共4页
Chinese Journal of Medical Imaging Technology
基金
国家自然科学基金(30870729
81071183)
国家重大科学仪器设备开发专项(2011YQ03011409)
关键词
体层摄影术
发射型计算机
单光子
磁共振成像
分子探针
多模态显像
Tomography, emission-computed, single photon
Magnetic resonance imaging
Molecular probes
Multi-modality imaging
