钙化在甲状腺结节MSCT诊断中的临床价值

Clinical value of calcification patterns in thyroid nodules in MSCT diagnosis

目的:探讨MSCT对甲状腺结节中的钙化灶的定性诊断价值。方法:回顾性分析了经手术病理证实的534个甲状腺结节,其中出现钙化99个。对于出现钙化的结节以病灶中心为圆心,钙化位于1/2半径内的定义为在中央,位于1/2以外的为在边缘,两种情况均出现的为混合型,观测钙化在结节中的位置。同时观测结节中钙化的形态、多少以及钙化大小的情况,并进行统计学分析。结果:甲状腺癌31个,结节性甲状腺肿56个,腺瘤12个。钙化完全位于结节中央的良性结节5个,恶性结节8个,良恶性甲状腺结节的钙化位置差异有统计学意义(χ2=5.817,P=0.016)。结论:甲状腺结节出现钙化,钙化位于结节中央时,结节为恶性的可能性大,而钙化的形态、多少以及钙化大小对于良恶性的鉴别没有意义。

Objective： To study the clinical value of calcification patterns in thyroid nodules in MSCT diagnosis. Methods： 534 cases of thyroid nodules confirmed by surgery and pathology were reviewed, including 99 cases with calcifica tion in the nodule. The location, size, morphology and amount of calcification were observed and analysed. The location of calcification was divided in central zone （the circle with inner half of the radius of the nodule） and peripheral zone （the re maining peripheral parts of the nodule）. Results： There were 31 cases of thyroid carcinoma, 56 cases of nodular goiter and 12 cases of thyroid adenoma. The calcification was observed completely in the central zone in 5 cases of benign nodules and in 8 cases of malignant nodules. There was statistical significant difference in the location of calcification between benign and ma lignant lesions （X2 = 5.817, P = 0.016）. Conclusion： When calcification situates in the central zone of thyroid nodule, the le sion is more possible malignant. The morphology,amount and size of the calcification in the thyroid nodule gives no help to the differential diagnosis of benign and malignant thyroid nodule.