平喘敷贴联合热疗治疗稳定期肺脾气虚型慢性阻塞性肺疾病随机对照研究

Randomized Controlled Trail of Pingchuan Cataplasm Combined with Hyperthermia Therapy for Stable Chronic Obstructive Pulmonary Disease with Qi Deficiency Syndrome of Both Lung and Spleen

目的观察平喘敷贴膏联合热疗对慢性阻塞性肺疾病(COPD)稳定期肺脾气虚证患者的临床疗效。方法选取中医证型属肺脾气虚证的稳定期COPD患者60例,随机分为治疗组和对照组,每组30例。在常规治疗基础上,治疗组予平喘敷贴联合发热贴治疗,对照组仅予模拟敷贴且不加发热贴治疗,治疗6周,观察患者治疗前后中医症状评分及治疗后首次急性加重时间。结果治疗组与对照组比较,可降低患者治疗后中医症状评分(F=9.843,P=0.003),延长治疗后首次急性加重时间间隔(F=4.451,P=0.040)。结论平喘敷贴联合热疗能改善患者症状,减少急性加重次数,达到治疗和预防COPD发作的目的。

Objective To investigate the clinical efficacy of Pingchuan cataplasm combined with hyperthermia therapy for stable chronic obstructive pulmonary disease （COPD） with qi deficiency syndrome of both lung and spleen. Methods Sixty patients of stable COPD with TCM syndrome of qi deficiency of both lung and spleen were selected and randomized into treatment group and control group, 30 cases in each group. Based on conventional treatment, the treatment group was treated by Pingchuan cataplasm combined with hyperthermia, and the control group was given analog stick applicator without additional heat treatment. After 6 weeks of treatment, the TCM symptom score and the time of the first exacerbation after treatment were observed. Results Compared with the control group, Pingchuan cataplasm can reduce the patients’ TCM symptom score （F=9.843, P=0.003）, and extend the interval of acute exacerbation after treatment （F=4.451, P=0.040）. Conclusion Pingchuan cataplasm combined with hyperthermia applicator can improve symptoms and reduce the frequency of acute exacerbation, thus can treat and prevent the acute exacerbation of COPD.