根尖周炎瘘管与根管内特殊细菌定植的相关性

Correlation studies on apical periodontitis with a fistula and colonization of pathogenic bacteria in root canal

目的探析慢性根尖周瘘管发生和根管内特殊细菌定植的相关性。方法选择2011年1月—2012年12月金华市中心医院慢性根尖周炎患者62例共62颗患牙,根据有无瘘管分为观察组有瘘型(n=30例)和对照组无瘘型(n=32例),均行根管治疗,髓腔预备和根管初预备后取根管内容物进行检测,对比2组样本的菌种类型。结果观察组哈夫尼菌属检出率100.00%(30/30)、黄褐二氧化碳噬纤维菌53.33%(16/30)、真杆菌属46.67%(14/30)、革兰氏阴性球菌60.00%(18/30)、卟啉单胞菌80.00%(24/30)、变黑普氏菌33.33%(10/30)、马氏棒杆菌80.00%(24/30)和口炎消化链球菌26.67%(8/30),显著高于对照组的75.00%(24/32)、21.88%(7/32)、15.63%(5/32)、28.13%(9/32)、34.38%(11/32)、3.13%(1/32)、43.75%(14/32)和3.13%(1/32),差异均具有统计学意义(均P<0.05)。结论慢性根尖周炎瘘管发生与哈夫尼菌属、黄褐二氧化碳噬纤维菌、真杆菌属、革兰氏阴性球菌、卟啉单胞菌、变黑普氏菌、马氏棒杆菌和口炎消化链球菌定植相关。

Objective To study the relationship between colonization of pathogenic bacteria in root canal and chronic api- cal periodontitis with fistula. Methods A total of 62 tooth in 62 cases of chronic apical periodontitis from January 2011 to December 2012 were studied. According to the presence of fistula, they were divided into observation group （30 cases with fistula） and control group （32 cases without fistula）. All patients received the root canal treatment. The root canal contents were sampled to test the bacterial types before the medullary cavity preparation and early root canal preparation. Results In the observation group, the positive rate of Hafnia was 100.00% （30/30） , Capnocytophaga oehraeea 53.33 % （ 16/30 ）, Eubacterium 46.67% （ 14/30 ） , gram negative coccus 60.00% （ 18/30 ） , Porphyromonas gingivali 80.00% （ 24/30 ） , Pre- votella nigreseens 33.33% （10/30）, Corynebaeterium maturchotii 80.00% （24/30）, Peptostreptoeoecus 26.67% （8/ 30） ,was significantly higher than the control group 75.00% （24/32） ,21.88% （7/32）, 15.63% （5/32） ,28.13% （9/ 32） ,34.38% （11/32） ,3.13% （1/32） ,43.75% （14/32） and 3.13% （1/32） ,respectively,the differences was statisti- cally significant（ P 〈 0.05 ）. Conclusion The chronic apical periodontitis with fistula has correlation with the coloniza- tion of Hafnia, Capnoeytophaga oehraeea, Eubacterium, gram negative coccus, Porphyromonas gingivali, Prevotella nigres- cens, Corynebaeterium maturchotii and Peptostreptoeoeeus in root canal.