摘要
目的探讨特发性卵巢早衰（POF）发病的危险因素及保护因素。方法选取确诊的特发性POF女性85例为研究组，同时选取卵巢功能正常的健康妇女100例为对照组，分别填写自制《特发性POF发病相关因素调查问卷表》及A、C型行为量表，对调查结果采用单因素、多因素Logistic回归法进行分析。结果多因素Logistic回归分析结果显示：家族史（OR=3．906，95％CI1．638～18．437）、化学物质接触史（OR=4．033，95％CII．172—13．987）、人工流产（OR=5．534，95％C11．679～18．479）、A型性格（OR=5．97，95％CI1．663～20．989）为特发性POF的危险因素，而经常锻炼身体（OR=0．103，95％C10．037～0．342）为其保护性因素。结论避免接触化学性有害物质及人工流产，保持良好心态，加强体育锻炼，有利于减少特发性POF的发病风险。
Objective To explore the risk factors and protective factors for idiopathic premature ovarian failure （POF）. Methods Our study included 85 patients with POF and 100 healthy women as a control group. All the recruits comple- ted detailed questionnaires. Results By the multiple logistic regression analysis, it was revealed that there were four sig- nificant risk factors for idiopathic POF： Family history（ OR = 3. 906,95% CI 1. 638 - 18. 437 ） , chemical substance expo- sure history（ OR = 4. 033,95% CI 1. 172 - 13. 987 ）, induced abortion （ OR = 5. 534,95% CI 1. 679 - 18. 479 ）, type-A personality （ OR = 5.97,95 % CI 1. 663 - 20. 989 ） , while, taking more exercises （ OR = O. 103,95 % CI O. 037 - 0. 342 ） was the protective factors. Conclusion Avoiding exposure to chemical substance exposure history and induced abortion, maintaining good mental status and taking exercises would be effective to the prevention of idiopathic POF.
出处
《中华全科医学》
2014年第4期613-614,共2页
Chinese Journal of General Practice
关键词
卵巢早衰
特发性
危险因素
保护因素
Premature ovarian failure
Idiopathic
Risk factors
Protective factors
