摘要
个体化治疗是指通过患者体内的有关药物作用靶点、路径、代谢等评估药物对患者可能的作用,提高治疗的针对性、避免反复尝试与不良反应,提高用药的安全性和有效性。通过药物敏感性基因检测,实现对结直肠癌化疗药物敏感性和疗效预测,进而优化治疗方案,提高疗效、减少无效治疗。结直肠癌患者选择化疗方案或靶向治疗之前进行药敏基因检测是实现个体化治疗的必经之路。
Individualized treatment to improve the pertinence, avoid repeated trial and adverse reactions, and increase the safety and efficacy through assessment of the possible action on patients through targets, paths, and metabolics of the medication. Drug sensitivity genetic testing can realize colorectal cancer chemo- therapy drug sensitivity and efficacy prediction, so as to optimize the treatment plan,improve the efficacy and reduce the ineffective treatment. Patients with colorectal cancer＇s drug-sensitive gene detection prior to chem- otherapy or targeted therapy is the only way to achieve individualized treatment.
出处
《医学综述》
2014年第5期810-813,共4页
Medical Recapitulate
关键词
基因检测
结直肠癌
治疗
Gene test
Colorectal cancer
Therapy
