两台分析仪C-反应蛋白检测结果比对研究

Comparison research of detection results about C- reactive protein between two analyzer

目的:探讨用免疫比浊法检测血清C-反应蛋白和乳胶免疫比浊法检测全血C-反应蛋白结果的可比性。方法:选取高中低新鲜血清标本,全血标本各20例,采用免疫比浊法分别测定C-反应蛋白的含量。参照美国临床实验室标准化协会NCCLS EP9-A2文件进行结果比对、偏倚分析,离群点检验、线性回归分析。结果:两台仪器检测结果的相关系数r2=0.972,相关性较好,C-反应蛋白检测结果偏差小,两种方法检测结果差异有显著统计学意义(P<0.01)。结论:乳胶免疫比浊法检测全血C-反应蛋白结果准确可靠,符合临床要求。

Objective：Investigation with immunonephelometry to detect the serum C - reactive protein and latex immunonephelometry to detect whole the blood C - reactive protein compara- bility of results. Methods：Select twenty fresh serum and the whole blood samples contain high low concentration, Use immunonephelometry to detect the content of C - reactive protein. According to National Committee for Clinical Laboratory Standards （NCCLS） document EP9-A2 to evaluate comparison , Bias Analysis,Test outliers, Linear regression analysis.Results：The correlation coefficient of two instrument test results is r~=0.972,is good,Testing results of two methods had significant statistical significance differcnce（P〈0.0l ）.The deviation about results of C - reactive protein is small. Conclusion：the testing results of C - reactive protein with latex immunonephelometry is accurate and reliable, Conform to the requirements of the clinical.