摘要
Two new eupodienone lignans, named gymnothelignan T （1） and gymnothelignan U （2） were isolated from the whole plants of endemic medicinal plant of Gymnotheca chinensis （Saururaceae）. The structures of the new compounds were elucidated by means of HRMS, 1D and 2D NMR. Compound I was tested for cytotoxic activity in HCT15, HCT116, A549, MCF-7 and HepG2 cells and exhibited no appreciable activity against these tested cell lines with IC50 values above 50 μmol/L.
Two new eupodienone lignans, named gymnothelignan T （1） and gymnothelignan U （2） were isolated from the whole plants of endemic medicinal plant of Gymnotheca chinensis （Saururaceae）. The structures of the new compounds were elucidated by means of HRMS, 1D and 2D NMR. Compound I was tested for cytotoxic activity in HCT15, HCT116, A549, MCF-7 and HepG2 cells and exhibited no appreciable activity against these tested cell lines with IC50 values above 50 μmol/L.
基金
financially supported by the grant from the National Natural Sciences Foundation of China (No. 30973634)
