常规磁共振成像与三维磁共振波谱对前列腺特异性抗原灰区患者鉴别诊断价值研究

MRI and MRS in the diagnosis of prostate cancer and BPH

目的：探讨常规磁共振成像（magnetic resonance imaging,MRI）联合三维磁共振波谱（magnetic resonance spectroscopy,MRS）成像对PSA灰区患者在前列腺癌与BPH的鉴别价值.方法：回顾性分析25例经病理证实的前列腺癌、20例前列腺增生PSA灰区患者进行MRI及MRS检查.MRS成像计算（cho＋ cre） /Cit的比值,比值大于0.99为前列腺癌的可疑波谱,将病灶的多体素取平均值,并与病理及其他磁共振方法进行对照.结果：MRI确诊率77.8％,MRS确诊率86.7％,MRI联合MRS确诊率95.6％.结论：MRI联合MRS用于临床诊断PSA范围在4～10ng/mL的患者,可以提高前列腺疾病的诊断率,但还需要前列腺活检以确定诊断.

Objectives： To explore the clinical value of using magnetic resonance imaging （MR/） combined with three -dimensional magnetic resonance spectroscopy （MRS） in gray area of PSA to confirm prostate cancer and benign prostatic hypertrophy （BPH）. Method： 25 cases of prostate cancer confirmed by pathology and 20 patients with hyperplasia of prostate PSA gray area were retrospectively analyzed by MILl and MRS examination. MRS imaging （cho ＋ ere）/Cit ratio was computed. The rate 〉 0. 99 was an indicator of prostate cancer. The average of multi - voxel proton was computed, and the results were compared with other magnetic resonance methods. Results： The diagnosis rate of MRI was 77.8%. The diagnosis rate of MRS was 86. 7%. The diagnosis rate of MRI combined with MRS was 95.6%. Conclusion： MRI combined with MRS used for clinical diagnosis of patients with 4 - 10 ng/ ml PSA can improve the diagnosis rate of prostate diseases, but prostate biopsy is needed to confirm the diagnosis.