微波加干扰素α-2b治疗120例尖锐湿疣的临床观察

Microwave combined with interferon α-2b in the treatment of condyloma acuminatum

目的:探究分析微波加干扰素α-2b对尖锐湿疣的临床治疗效果,进而为提高尖锐湿疣临床治疗有效率提供有效依据。方法:选取自2010年7月至2012年6月在我院接受临床治疗的尖锐湿疣患者120例,采取随机数字表法将其分为对照组与观察组,其中对照组患者单纯采取微波疗法,观察组患者则采取微波加干扰素α-2b联合疗法,比较两组患者临床治疗有效率与术后复发率,并做好有关数据的统计分析工作。结果:观察组患者临床有效率95.0%,显著优于对照组78.3%,P<0.05;而且通过随访调查,比较两组患者复发率,观察组4个月、8个月、12个月的复发率分别为1.7%、5.0%、8.3%,同样显著优于对照组6.7%、18.3%、31.7%,P<0.05,相关比较均具有统计学意义。结论:采取微波加干扰素α-2b治疗尖锐湿疣,不仅可以有效提高临床治疗有效率,还可以确保患者远期生活质量,降低复发率,临床价值显著,值得推广应用。

Objectives： To explore the efficacy of microwave combined with interferon a -2b in the treatment of condyloma acuminatum, and to provide evidence of effective treatment for condyloma acuminatum. Method： We selected 120 patients with condyloma aeuminatum who were admitted into our hospital from July 2010 to June 2012, and randomly divided them into the control group and the observation group. The control group simply took the microwave therapy while the observation group received microwave treatment combined with interferon a - 2b. The two groups are compared in terms of treatment efficacy and postoperative recurrence. Results ： The efficacy rate for the observation group was 95.0% , significantly higher than the control group 78. 3% （ P 〈 0. 05 ） ; The follow - up study indicated the recurrence rates in the observation group were respectively 1.7%, 5.0%, 8. 3% after 4 months, 8 months, 12 months, significantly lower than the rates in the control group （6. 7%, 18.3%, 31.7%, P 〈 0. 05 ）. Conclusion： Microwave eombined with interferon a- 2b can significantly enhance the clinical efficacy for the treatment of condyloma aeuminatum. The treatment proves to be satisfactory in improving the long - term life quality of patients, and in reducing the recurrence rates.