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肿瘤标志物CA125、AFP及CEA检测用于卵巢癌诊断的临床价值分析 被引量:1

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摘要 目的:观察血清肿瘤标志物CA125、AFP及CEA对卵巢癌诊断的临床价值。方法选取2010年4月~2012年5月于本院进行卵巢癌治疗的50例卵巢癌患者为研究对象,均空腹静脉采血,血清CA125、AFP及CEA测定采用全自动电化学发光分析仪进行相关指标检测。结果与健康对照者作比较,卵巢癌患者CA125、AFP及CEA水平明显增高,差异有统计学意义(P〈0.05)。结论卵巢癌患者的血清肿瘤标志物CA125、AFP及CEA三项联合检测提高了灵敏度和准确性,减少漏诊,对卵巢癌的早期诊断,治疗和预后起到重要的积极意义.
作者 刘美华
出处 《中国实用医药》 2014年第3期43-44,共2页 China Practical Medicine
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  • 1翁彬,孟庆宝,王雷萍,段纯.肿瘤标志物联合检测诊断卵巢癌的实验研究[J].医学临床研究,2006,23(4):486-487. 被引量:17
  • 2Maeda T, Inoue M, Koshiba S, et al. Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125(MUC16) [J]. J Biol Chem, 2004, 279( 13): 13174-13182.
  • 3Benjapibal M, Neungton C. Pre-operative prediction of serumCA125 level in women with ovarian masses [J]. J Med Assoc Thai, 2007, 90( 10): 1986-1991.
  • 4Menon U, Skates SJ, Lewis S, et al. Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer [J]. J Clin Oncol, 2005, 23 (31 ): 7919-7926.
  • 5Moore RG, Brown AK, Miller MC, et al. The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass [J ]. Gynecol Oncol, 2008, 108 (2):402-408.
  • 6Zhang Z, Yu Y, Xu F, et al. Combining multiple serum tumor markers improves detection of stage I epithelial ovarian cancer [J ]. Gynecol Oncol, 2007, 107(3): 526-531.
  • 7Visintin I, Feng Z, Longton G, et al. Diagnostic markers for early detection of ovarian cancer [J]. Clin Cancer Res, 2008, 14 (4): 1065-1072.
  • 8Bertenshaw GP, Yip P, Seshaiah P, et al. Multianalyte profiling of serum antigens and autoimmune and infectious disease molecules to identify biomarkers dysregulated in epithelial ovarian cancer [J]. Cancer Epidemiol Biomarkers Prey, 2008, 17(10): 2872-2881.
  • 9Drapkin R, von Horsten HH, Lin Y, et al. Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas [J]. Cancer Res, 2005, 65 (6): 2162-2169.
  • 10Ho M, Hassan R, Zhang J, et al. Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients [J]. Clin Cancer Res, 2005, 11 ( 10): 3814-3820.

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