肝豆状核变性87例脑核磁共振成像表现特点分析

MRI ANALYSIS OF 87 PATIENTS WITH HEPATOLENTICULAR DEGENERATION

目的探讨核磁共振成像(MRI)在肝豆状核变性中的诊断价值。方法收集87例肝豆状核变性MRI结果,并进行分析。结果 87例中脑部MRI出现异常信号66例(75.9%),分布频率最高的是豆状核(59例,89.4%),其次是丘脑、大脑脚、桥脑等部位;15例经治疗后复查有12例异常信号范围变小或消失。结论脑部MRI是肝豆状核变性诊断的有力佐证,MRI检查可作为确诊和评估疗效的有效手段。

Objective To evaluate MRI in diagnosing hepatolenticular degeneration（HLD）. Methods Pretreatment brain MRI were performed in 87 cases with HLD. 15 patients were treated were followed up. Results Abnormal signals on brain MRI were seen in 66 cases（75. 9%）, distribution was the highest frequency of lentiform nucleus（59,89.4% ）, thalamus, followed by cerebral peduncle and pons and other parts. On the follow-up MRI of 15 patients, brain lesions of 12 patients shrunk or disap-peared. Conclusion MRI is an effective means to the diagnosis and evaluation of treatment effect.