摘要
目的:评价昂丹司琼联合地西泮防治顺铂化疗所致恶心、呕吐的疗效。方法:将81例患者随机分为A、B两组,A组化疗前应用昂丹司琼8 mg,2次/d,静脉注射,地西泮10 mg,1次/d,静脉注射;B组化疗前单用昂丹司琼8 mg静脉注射,2次/d,对两组药物的疗效进行比较。结果:两组药物控制延迟性呕吐的有效率比较差异有统计学意义(P<0.05),在控制延迟性恶心、呕吐方面,昂丹司琼联合地西泮优于单用昂丹司琼。结论:昂丹司琼联合地西泮可作为预防化疗所致恶心、呕吐的常规方案。
Objective：To appraise the therapeutic effect of Ondansetron combined with Diazepam in treatment of Cisplatin-induced nausea and vomiting.Method：81 patients were randomly divided into A,B groups. Before chemotherapy, in Group A,Ondansetron 8 mg,2 times/d,intravenous injection,and Diazepam 10 mg,1 time/d,intravenous injection;Group B was treated with intravenous ondansetron 8 mg,2 times/d.The effect of two groups were compared.Result：Efficiency of delayed nausea and vomiting of two groups was statistically significant difference,the effect of ondansetron combined with Diazepam was superior than ondansetron.Conclusion：Ondansetron combined with Diazepam can be used as conventional scheme for prevention of chemotherapy-induced nausea and vomiting.
出处
《中国医学创新》
CAS
2014年第8期38-40,共3页
Medical Innovation of China
关键词
昂丹司琼
地西泮
顺铂
化疗
呕吐
Ondansetron
Diazepam
Cisplatin
Chemotherapy
Vomiting
