血清结核抗体检测对肺结核的诊断价值

The Value of Detection of Serum Anti Mycobacterium Tuberculosis Antibody in Diagnosis of Tuberculosis

目的:评价血清结核抗体对肺结核的临床诊断价值。方法:选取本院肺部疾病住院患者2238例,其中肺结核患者799例为观察组,除肺结核外其他肺部疾病患者1439例为对照组。分别用抗酸染色法查找抗酸杆菌,金标法对结核抗体进行检测并观察其结果。结果:观察组抗体阳性率43.05%,对照组为14.38%,两组比较差异有统计学意义(P<0.01)。痰涂片阳性患者结核抗体阳性率53.64%,高于痰涂片阴性患者结核抗体阳性率33.88%,比较差异有统计学意义(P<0.01)。结论:血清结核抗体检测对肺结核诊断具有一定的临床价值。

Objective：To explore the diagnosis value of serum anti mycobacterium tuberculosis antibody in pulmonary tuberculosis patients. Method：2238 lung disease patients in the hospital were selected,including 799 cases of pulmonary tuberculosis patients as the observation group and other 1439 cases as the control group. Than acid-fast bacilli were detected by staining with acid and tuberculosis antibody were detected by the gold standard method. The results between the two groups were compared. Result：The antibody positive rate of the control group was 14.38%while the observation group was 43.05%,and the difference between the two groups were statistically significant（P〈0.01）. The antibody positive rate of the sputum smear-negative patients were 33.88%while the sputum smear-positive patients were 53.64%,and the difference between the two groups were statistically significant（P〈0.05）.Conclusion：Detection of serum anti mycobacterium tuberculosis antibody has some clinical value in diagnosis of pulmonary tuberculosis.