吲达帕胺联合依那普利治疗糖尿病合并高血压的可行性研究

Feasibility of Indapamide Combined with Enalapril in the Treatment of Diabetes Mellitus Complicated with Hypertension

目的:分析吲达帕胺联合依那普利治疗糖尿病合并高血压的临床效果及可行性。方法:随机将我院收治的70例患者分为对照组和观察组,对照组主要采用依那普利治疗,观察组在对照组治疗的基础上加用吲达帕胺治疗,观察两组患者血糖、血钾、血压水平及其治疗效果。结果:血钾、血糖方面,两组患者治疗前后检测比较,P>0.05;治疗后,观察组血糖低于对照组,两组比较,P<0.05;血压方面,两组患者的舒张压和收缩压均有所下降,观察组下降效果优于对照组,两组比较,P<0.05;观察组血压控制的总有效率为85.71%,对照组为65.71%,两组比较差异显著,具有统计学意义(P<0.05)。结论:对糖尿病合并高血压患者行吲达帕胺联合依那普利治疗效果显著,不良反应少,安全性和可行性较高。

Objective： To analysis the clinical effects and feasibility of indapamide combined with enalapril in the treatment of diabetic mellitus complicated with hypertension.Methods： A total of 70 cases in our hospital were divided into control group and observation group. Patients in the control group were treated with enalapril, and patients in the observation group were treated with indapamide combined with enalapril. The level of blood glucose,serum potassium,blood pressure and effects were observed. Results： There are no significant difference on the level of blood potassium and blood glucose in the two groups（P〉0.05）. After treatment, the blood pressure in the observation group was lower than that of the control group（P〈0.05）. The total effective rate was 85.71% in the observation group,and 65.71% in the control group. The differences between the two groups were statistically significant （P＜0.05）.Conclusion： Indapamide combined with enalapril has remarkable effect for the treatment of diabetes mellitus complicated with hypertension.