外伤性大面积脑梗塞危险因素分析及临床对策研究

RISK FACTORS ANALYSIS OF TRAUMATIC LARGE-AREA CEREBRAL INFARCTION AND CLINICAL COUNTERMEASURES

目的探索造成外伤性脑梗塞的相关危险因素及最佳治疗和预防方法。方法对外伤性脑梗塞患者进行回顾性分析,采用病例对照研究,按不同治疗分组分为手术组和非手术组,增容扩血管组和普通治疗组。比较两组患者的临床疗效,并对影响疗效的多因素进行分析。结果增容组脑梗塞发生率低于限液组,非手术组脑梗塞发生率低于手术组,差异均有统计学意义(P<0.05),脑梗塞发生后超早期给予干预治疗效果好。结论早期限制液体的入量、高颅压、低灌注及血管牵拉损伤是导致脑梗塞发生的重要原因。

Objective To explore the risk factors of traumatic cerebral infarction and its prevention and treatment. Methods The patients with traumatic cerebral infarction were retrospectively analyzed. With the method of case control study, the patients were divided into surgical group of capacity expansion of blood vessels and the non-surgical treatment common group. The clinical efficacy of two groups of patients was compared and the factors influencing the curative effect were analyzed. Results Significantly lower incidence of cerebral infarction was found in the group of capacity expansion than in the group of restriction of fluid （ P 〈0.05）, and the incidence in the surgical group was lower than in the non-surgical treatment group（ P 〈0.05）. Early intervention could produce good curative effect. Conclusion Early fluid restriction, high intracranial pressure, hypoperfusion and vascular pull injury are the important risk factors of cerebral infarctlon.