复方丹参滴丸联合双环醇治疗酒精性肝病临床效果观察

Effect of compound Danshen dripping pill plus bicyclol on alcoholic liver disease

目的探讨复方丹参滴丸联合双环醇治疗酒精性肝病的临床效果。方法将70例酒精性肝病患者随机分为2组,对照组35例,给予双环醇治疗;观察组35例,给予双环醇加复方丹参滴丸口服,2组均连续用药16周。观察2组治疗前后肝功能指标及肝纤维化指标。结果 2组治疗后丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、γ-谷氨酰转肽酶(GGT)、碱性磷酸酶(ALP)差异无明显统计学意义(P>0.05);治疗组总胆红素及肝纤维化指标下降幅度明显优于对照组,差异有统计学意义(P<0.05)。2组治疗期间均未见明显不良反应。结论复方丹参滴丸联合双环醇治疗酒精性肝病效果更好,不良反应少,值得临床推广。

Objective To investigate the therapeutic effect of Compound Danshen dripping pill plus bicyclol on alcoholic liver disease. Methods Seventy in-patients of alcoholic liver disease were divided into treatment group and control group randomly,35 cases in control group were given bicyclol,and 35 cases in treatment group were added extraly Compound Danshen dripping pill. The parameters of their liver function and hepatic fibrosis were compared before and after the treatment for 16 weeks. Results Two groups have no statistically significant in reducing the indicators of ALT、AST、GGT、ALP（P＆gt;0.05）,The serum TBil、HA、LN、PCⅢandⅣC in treatment group decreased more significantly than the control group （P＆lt;0.05）,The two groups during treatment showed no obviously adverse reactions. Conclusion Therapeutic effect of Compound Danshen dripping pill plus bicyclol on alcoholic liver disease show better ,fewer adverse reactions,worthy of clinical promotion.