摘要
妊娠期应用精神药物可导致20％-30％的新生儿出现撤药症状,临床表现主要包括中枢神经系统兴奋症状、胃肠道功能失常症状、呼吸系统症状、自主神经方面症状体征等.由于新生儿精神药物撤药综合征临床表现无特异性,容易误诊,所以应详细询问母亲病史,特别是孕期用药史,严密观察临床症状,采用临床量表进行评定,进行有关的实验室及其他检查,并排除其他疾病.治疗上支持疗法至关重要,病情严重时可给予苯巴比妥等药物.
The use of psychotropic medications during pregnancy causes withdrawal symptoms in 20％ ～ 30％ of newborns.The main clinical features of neonatal psychotrpic withdrawal syndrome are neurologic excitability,gastrointestinal dysfunction,respiratory symptoms and autonomic nervous dysfunctions.Because the clinical features of neonatal psychotropic withdrawal syndrome are non-specific,it was easily misdiagnosed.We should get the details of disease history in mothers,especially medication using during pregnancy,closely observe clinical symptoms,assess patients by the neonatal drug withdrawal scoring system,make laboratory test and other accessory examination,exclude other diseases.Supportive treatment is essential to this disease,pharmacologic therapy （such as phenobarbital） could be adopted if necessary.
出处
《国际儿科学杂志》
2014年第2期153-157,共5页
International Journal of Pediatrics
关键词
撤药综合征
精神药物
新生儿
Withdrawal syndrome
Psychotropics
Newborn
